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Introduction Atrial fibrillation AF is the
2019-05-23
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia managed in clinical practice and the most common arrhythmia requiring hospitalization [1,2]. Thromboembolism occurs with similar incidence, regardless of the form of AF [3,4]. AF management includes anticoagulation to prev
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Prior case reports have described hematological remission in
2019-05-23
Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic vorinostat on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we re
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There is also a pressing need to change the
2019-05-23
There is also a pressing need to change the way societal and mitotic inhibitor progress is measured to more accurately reflect an ecosocial approach to health. We are thus interested in applying the Happy Planet Index (HPI) at a community as well as at a national level. The HPI, an innovative measu
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BMN673 Air pollution also has a
2019-05-23
Air pollution also has a substantial effect on the wellbeing of people worldwide. This pollution can consist of sulfur dioxide, ozone, nitrogen dioxide, and fine-particulate BMN673 of less than 2·5 μm in diameter (PM). 92% of the global population is exposed to higher-than-recommended concentrations
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Assim como forma de ep logo que ligue
2019-05-22
Assim, como forma de epílogo que ligue essa ideia central defendida por nós, citamos o editorial de lançamento da revista Araucaria de Chile, que, em 1978, afirmava: Bien se sabe que Chile no es una isla ni su tragedia combate un accidente ni un caso de excepción en América Latina. Su situación se
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Los dedos son las cuatro mil verdades
2019-05-22
Los dedos son las cuatro mil verdades vistas por los ojos de las moscas. La labor del escritor, entonces, se pone Immunology Inflammation Compound Library la altura de la labor del detective: encontrar los diez dedos, descubrir el cuerpo flotando en el agua, dar con una cabeza que yace en el fondo d
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br Identidade negra e quilombola O uso da
2019-05-22
Identidade negra e quilombola O uso da expressão “remanescentes” para classificar os agrupamentos negros, enquanto unidades que guardam correspondência histórica com os quilombos, motivou reflexões sobre seu significado. Adotamos o entendimento de que ao contrário do sentido de sobra ao qual pode
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br Authorship br Conflict of interest
2019-05-22
Authorship Conflict of interest Acknowledgments The Leukemia & Lymphoma Society supported CRC with a Scholar in Clinical Research award (2400-13). This work was supported by the Gatorade Trust from the University of Florida Department of Medicine. Introduction Klinefelter syndrome (KS),
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br AML therapies with curative intent br
2019-05-22
AML therapies with curative intent Alternative treatment strategies Targeted therapies: the new kids on the block The recognition of specific mutations as genetic drivers or facilitators of AML has led to the development of new inhibitors and targeted treatment options. New promising drug c
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Introduction Acute myeloid leukemia AML is a rare disease
2019-05-22
Introduction Acute myeloid leukemia (AML) is a rare disease afflicting annually 3–4 persons per 100,000 individuals. With a median age at diagnosis of 67 years, this disease is far more common in the elderly [1]. In this age group, AML has a particularly dismal outcome with less than 5% of the pati
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Phosphorus is essential for organic activity such
2019-05-22
Phosphorus is essential for organic activity such as cellular signal transduction, membrane transport, mineral metabolism, and farnesyl diphosphate synthase exchange [1]. Bone and teeth store 80% of the total body phosphorus. Intracellular phosphorus consists of the form of organic compounds such a
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Lead fracture was observed in of
2019-05-22
Lead fracture was observed in 4 of 1092 leads (0.37%); verified and incomplete lead fractures were observed in three (0.27%) and one lead (0.09%), respectively. All these fractures occurred in leads implanted by the SVP method; no fractures were observed in leads implanted by the CVC method (p Disc
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br Control of visceral leishmaniasis requires access to low
2019-05-22
Control of visceral leishmaniasis requires access to low-cost, safe, and effective treatment. Amphotericin causes infusion-related fever, rigor, and nephrotoxicity, limiting its use. Ambisome—a liposomal amphotericin manufactured by Gilead—is better tolerated and is effective as a single dose. How
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br Results and discussion In this study the np
2019-05-21
Results and discussion In this study, the np9 and gag mRNA expression was established for 25 patients with CLL (Fig. 1). We found that the transcriptional activity of HERV-K np9 gene in CLL patients was higher than in PBMCs from healthy donors. The results revealed that 18 out of 25 CLL patients
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br The Millennium Development Goals on health have expanded
2019-05-21
The Millennium Development Goals on health have expanded access to basic health interventions to millions of people in low-income and middle-income countries (LMICs). However, access alone will not be sufficient to meet the Sustainable Development Goals (SDGs) if health systems cannot provide high
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