• AMP activated protein kinase AMPK is a key

  2023-08-29

  

  AMP-activated protein kinase (AMPK) is a key cellular energy sensor that maintains energy homeostasis at the cellular and whole-organism level (Hardie et al., 2012). Functionally, the AMPK pathway sustains adenosine triphosphate (ATP) production through activation of fatty BCTC oxidation and autoph

• br Conclusion br Conflict of

  2023-08-29

  

  Conclusion Conflict of interest Acknowledgements Introduction Human salivary aldehyde dehydrogenase (hsALDH) (E.C. 1.2.1.5) is the first line of defence against toxic aldehydes in the oral cavity. HsALDH is primarily a dimeric, class 3 ALDH (ALDH3A1) specific for aromatic and long/medium

• Within the PARP family TIPARP is most evolutionarily

  2023-08-29

  

  Within the PARP family, TIPARP is most evolutionarily conserved with PARP12 (ARTD12) and PARP13 (ARTD13) [27,28,41]. All three proteins contain at least one RNA-type CCCH zinc finger domain, a poly-ADP-ribose binding WWE domain and a PARP catalytic domain (Fig. 1). PARP13 is catalytically inactive,

• br Introduction br Rac dependent ROS

  2023-08-28

  

  Introduction Rac1-dependent ROS and Myelin Basic Protein (87-99) receptor regulation in neuronal functions NOX-mediated ROS have an important role as physiological messengers. One remarkable example regarding such a function is during axonal formation. In this line, increased p40phox/NOX2 lev

• ion channel br Experimental section br Conflicts of interest

  2023-08-28

  

  Experimental section Conflicts of interest Acknowledgments This work was partly supported by INSA-Rouen, Rouen University, CNRS, Labex SynOrg (ANR-11-LABX-0029), Région Haute-Normandie. Introduction A key component of the integrated management of key pests such as codling moth (Cydia po

• Introduction hydroxytryptamine HT is found throughout the bo

  2023-08-28

  

  Introduction 5-hydroxytryptamine (5-HT) is found throughout the body and influences smooth muscle activity in various tissues including the intestine, vasculature and urinary what does the cytoskeleton do (Kim and Camilleri, 2000, Klarskov and Horby-Petersen, 1986, Mohammad-Zadeh et al., 2008). The

• br Phosphorylation of P c Initial studies In addition

  2023-08-28

  

  Phosphorylation of P450c17 – Initial studies In addition to the molar ratio of POR to P450c17 and the allosteric action of cytochrome b5, a third factor that governs 17,20 lyase activity is the serine/threonine (Ser/Thr) phosphorylation of P450c17 itself. In a search for post-translational factor

• Despite the growing knowledge surrounding the

  2023-08-28

  

  Despite the growing knowledge surrounding the link between ATX and cholestatic pruritus in PBC, it remains unclear if the role of the ATX-LPA signaling axis includes lymphocytes homing in the liver of PBC, and if the resulting inflammation is associated with PBC pruritus (Fig. 3). PBC is characteriz

• There are no studies documented

  2023-08-28

  

  There are no studies documented the role of RAS in the differentiation of MSCs into IPCs but there are previous studies indicating that Ang II receptors exhibit opposing actions on MSCs differentiation, into other cell types rather than IPCs. The blockade of AT2R was reported to suppress MSCs differ

• Di ethylhexyl phthalate DEHP is one

  2023-08-28

  

  Di-(2-ethylhexyl) phthalate (DEHP) is one of the most widely used environmental chemicals in the production of polyvinyl chloride. After CCT241533 into human body, DEHP can be converted to the metabolite mono-ethylhexyl phthalate (MEHP), which has higher toxicity than DEHP and can influence reproduc

• To examine whether the interaction between

  2023-08-28

  

  To examine whether the interaction between mGlu7 and α1-adrenergic receptors could be confirmed at a behavioural level, we performed the FST in mice. This test has value in predicting the antidepressant-like effect of drugs or environmental manipulations (Krishnan and Nestler, 2008, Krishnan and Nes

• Using constant potential amperometry and electrochemical

  2023-08-26

  

  Using constant potential amperometry and electrochemical enzyme-based biosensors selective for choline—and, therefore, an accurate readout of Go 6983 release (Baker et al., 2015; Bruno et al., 2006a; Parikh et al., 2004, 2007)—tonic and phasic release of acetylcholine were measured simultaneously in

• br Free entry equilibrium At stage of the game n

  2023-08-26

  

  Free entry equilibrium At stage 2 of the game, n ≥ 2 firms simultaneously decide whether or not to enter the industry. Market entry involves a sunk fixed cost f > 0, which we assume cannot be subtracted from the tax base. Our assumption reflects that deductions of market entry costs are often inc

• Ebastine synthesis br lipoxygenase pathway in brain aging an

  2023-08-26

  

  5-lipoxygenase pathway in Ebastine synthesis aging and alzheimer’s disease 5LO is found throughout the central nervous system, in both neuron and glia cells (Farias et al., 2007). However, its expression levels are highest in the cortex and hippocampus areas, two regions that are particularly vul

• Taniyama et al reported a female with infertility

  2023-08-26

  

  Taniyama et al. reported a female with infertility who had a homozygous T-to-A transversion at nucleotide position g.2472 in exon 3 of the CYP17A1 gene (mutation Y201N) and decreased 17-hydroxylase and 17,20-lyase activities of IVF 2449 was initiated using dexamethasone to control adrenal P product

15638 records 248/1043 page Previous Next First page 上5页 246247248249250 下5页 Last page