• br Conclusion A hybrid technique combining Dynesys stabiliza

  2018-11-14

  

  Conclusion A hybrid technique combining Dynesys stabilization and interbody fusion can achieve successful interbody fusion, and maintain ROM in the bridged segment and thus improve clinical outcomes. However, it may decrease ROM in the global segment and cause hypermobility in the adjacent segmen

• The second cell type appeared to

  2018-11-14

  

  The second cell type appeared to be a cardiac mesenchymal/fibroblast-like cell that was CD90+/ISL1low/Periostinhi and capable of forming SMCs and ECs and partial differentiation into cardiac protein-expressing cells without sarcomere formation. CD90+ clones demonstrated higher expression of fibrobla

• We provide evidence that RUNX

  2018-11-14

  

  We provide evidence that RUNX1 has a role in early mesendodermal differentiation of hESCs through regulation of cell migration and adhesion, as indicated by impairment of these processes upon RUNX1 depletion. These findings are consistent with the emerging role of RUNX1 in controlling cell motility

• CaO contained in ash from

  2018-11-14

  

  CaO contained in ash from waste, possess excellent catalytic properties such as high basic strength and tolerance of high FFA oil, less environmental hazard impacts due to its low solubility in methanol (Suppes et al., 2004; Liu et al., 2008; Lee et al., 2009; Adewuyi et al., 2012; Khemthong et al.,

• Activation of the proto oncogene c myc

  2018-11-14

  

  Activation of the proto-oncogene c-myc is associated with cellular growth and proliferation programs (Dang, 2013) and is therefore an important feature of cancer initiation and maintenance (Gabay et al., 2014). Furthermore, c-myc induces the expression of telomerase reverse transcriptase (TERT) and

• Vitamin D deficiency is associated with food sensitization

  2018-11-14

  

  Vitamin D deficiency is associated with food sensitization (Baek et al., 2014), as well as IgE-mediated food allergy (Allen et al., 2013). Infants from Australian-born parents with vitamin D insufficiency had increased likelihood of egg and peanut allergy (Allen et al., 2013). By contrast, elevated

• Remarkable progress has been made in the treatment of ALL

  2018-11-14

  

  Remarkable progress has been made in the treatment of ALL. Currently, the five-year overall survival rates exceed 85% in pediatric patients in developed countries (Pui et al., 2015), but remain less than 45% in adults (Jabbour et al., 2015; Bassan and Hoelzer, 2011).The poor outcome in adults has be

• Lung cancer is the most common

  2018-11-14

  

  Lung cancer is the most common cancer in US and worldwide (Centers for Disease Control and Prevention and National Center for Health Statistics, 2013; American Cancer Society, 2014), and the survival rate is low (Howlader et al., 2013). Most cases (90%) of lung cancer are attributable to smoking (Ge

• Regarding the prognostic value of

  2018-11-14

  

  Regarding the prognostic value of CTC, detection of CTCs over the threshold value (CTC+ patients) in both the FCMC and CellSearch system was a worse prognostic factor in this study. The significant point that needs to be noted here is that the hazard ratio between CTC+ and CTC− patients using the FC

• The extracellular matrix ECM is important for the integrity

  2018-11-14

  

  The extracellular matrix (ECM) is important for the integrity of the aortic wall and mutations in ECM genes such as Fibulin-4 and Fibrillin-1 hence lead to aneurysm formation. Genetic studies in Fibulin-4 and Fibrillin-1 mutant mice implicated dysregulation of the TGF-β pathway as an important hallm

• br Materials Methods br Results We sequenced

  2018-11-14

  

  Materials & Methods Results We sequenced the exomes of 59 Greek (GR) and 15 German (DE) patients with validated bacterial sepsis/organ dysfunction according to the new Sepsis-3 definition (Seymour et al., 2016; Shankar-Hari et al., 2016; Singer et al., 2016). Each cohort included two groups of

• Traditionally serologic assays were designed to

  2018-11-14

  

  Traditionally, serologic assays were designed to detect SB203580 manufacturer against flavivirus structural proteins, especially viral E protein in the context of virions. A number of previous studies suggest that antibodies against flavivirus nonstructural proteins may be virus-type specific (Garci

• Palivizumab an antibody drug targeting antigenic

  2018-11-14

  

  Palivizumab, an antibody drug targeting antigenic site II of the RSV fusion protein (F protein), is available for the prevention of severe RSV illness in certain infants and children who are at high risk. The drug can help prevent development of serious RSV diseases, yet with limited efficacy (Groot

• br Introduction Influenza comprises a substantial portion of

  2018-11-14

  

  Introduction Influenza comprises a substantial portion of morbidity and mortality caused by acute respiratory infections, which are the fourth leading cause of death and the second highest cause of years of life lost (Organization, 2014; Radin et al., 2012; Nair et al., 2011). Severe influenza di

• BCG has been integrated into the Expanded Immunization

  2018-11-14

  

  BCG has been integrated into the Expanded Immunization Program of WHO since 1974 and neonatal vaccination with BCG is still used to prevent TB in countries with a high burden of TB (Marais et al., 2016). Correspondingly, adolescents and adults with LTBI always occur epidemiologically following inocu

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