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In advanced GIST patients where
2019-05-15
In advanced GIST patients where a course of treatment of Imatinib is interrupted by disease progression, subsequent rechallenge with Imatinib restored tumor control in most patients. In the prospective BFR14 trial, 25 patients with disease progression after interruption of one year of treatment rest
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The finding that baseline VEGF in the Zamboney study was
2019-05-15
The finding that baseline VEGF in the Zamboney study was not associated with clinical outcomes are in EPZ-6438 to other published studies. VEGF was previously shown to be associated with better treatment outcomes in metastatic breast cancer patients treated with bevacizumab [26,31]. This discrepanc
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br Al comienzo de Elizabeth Corral afirma que la escritura
2019-05-15
Al comienzo de , Elizabeth Corral afirma que “la escritura de Sergio Pitol tiene una relación orgánica con otras artes” (11). El resto del libro es la comprobación de esta tesis, un recorrido abiertamente personal en el que destacan el ingenio de la mirada y la lucidez para desmenuzar cada uno de
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As la historia a la vez ejemplar e
2019-05-15
Así, la historia, a la vez ejemplar e ilustrativa, es un elemento aglutinador de la identidad del pueblo mexicano pues conforma la narración unificadora necesaria para fusionar, en una identidad única, a la sociedad mexicana. Por ello, para Vigil, la enseñanza de la historia convertiría “a los habit
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thymidine phosphorylase inhibitor Currently RFCA is indicate
2019-05-14
Currently, RFCA is indicated if pharmacologic therapies are unsuccessful [41]. Myocardial substrates for reentrant VT and/or the origin of focal VT are the ablation target for monomorphic VT storms. Although ablating multiple and unstable VTs is challenging, modern computerized mapping and catheter
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br Case report In July a year old man visited
2019-05-14
Case report In July 2010, a 64-year-old man visited the outpatient clinic of National Taiwan University Hospital due to progressive enlargement of right submandibular mass for months. A nasopharyngeal tumor was found by fiber optic exam, and biopsy showed a non-keratinizing undifferentiated carci
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PPCL were associated with a very
2019-05-14
PPCL were associated with a very poor prognosis. The median survival duration according to published small trials was short, ranging from 7 to 13 months, with less than 10% of patients having a median survival of more than 5 years. In the largest recently published epidemiological study, the median
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It is noted that in this study BrS patients
2019-05-14
It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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mature testes In patients with systolic heart failure and a
2019-05-13
In patients with systolic heart failure and a wide QRS complex, cardiac resynchronisation therapy (CRT) using left ventricular (LV) pacing has been shown to enhance survival, reduce heart failure hospitalisation and enhance exercise capacity in patients with all mature testes of heart failure. The
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br Conclusions br Study limitations br Conflict of interest
2019-05-13
Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum b
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br Conclusions br Conflict of
2019-05-13
Conclusions Conflict of interest Introduction Gastrointestinal stromal tumor (GIST) arises from the mesenchymal tissue of the gastrointestinal tract. The annual incidence of this condition is 7 cases per million people in the West. However, the incidence could in fact be higher in Asian pop
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br Conflict of interest br
2019-05-13
Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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Phosphorus is essential for organic activity such as cellula
2019-05-13
Phosphorus is essential for organic activity such as cellular signal transduction, membrane transport, mineral metabolism, and rgs protein exchange [1]. Bone and teeth store 80% of the total body phosphorus. Intracellular phosphorus consists of the form of organic compounds such as adenosine tripho
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These results have to be
2019-05-13
These results have to be interpreted with respect to present trends in age at childbearing. Worldwide, adolescent fertility rates fell from 71 to 52 per thousand women aged 15–19 years between the 1970s and the 2000s. This endopeptidase was seen in all regions, with the possible exception of Latin A
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En raz n del desarrollo que la oposici n
2019-05-13
En razón del desarrollo que la oposición entre el individuo y la colectividad ha cobrado en Occidente, y cada vez es más aguda, se han entendido o malentendido las demandas de los pueblos indígenas como contrarias agomelatine los derechos individuales, pero tal perspectiva es reduccionista, ya que n
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