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In patients with systolic heart failure and a wide QRS
2019-05-18
In patients with systolic heart failure and a wide QRS complex, cardiac resynchronisation therapy (CRT) using left ventricular (LV) pacing has been shown to enhance survival, reduce heart failure hospitalisation and enhance exercise capacity in patients with all 2-MPPA of heart failure. The patien
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In addition to inducing IKs dysfunction through dominant neg
2019-05-18
In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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Las colaboraciones de Woinoff conforman el ltimo v
2019-05-18
Las colaboraciones de “Woinoff ” conforman el último vértice de la constelación intelectual que, protein kinase nuestro juicio, pudo haber ayudado en el cambio intelectual de Bilbao. En ellas, el pretendido “atraso” se vuelve reserva moral desde la cual la democracia radical europea puede pensar de
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Despertar de la ilusi n le significa a Villoro su
2019-05-18
Despertar de la “ilusión” le significa KY02111 Villoro su tránsito a la crítica de las filosofías de J. Rawls yJ. Habermas, afirma que no son pertinentes para el caso de nuestra condición social y política, ya que a pesar de las diferencias importantes entre sus teorías, ambas parten “de la idea de
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br El nacionalismo entendido como
2019-05-18
El nacionalismo, entendido como una ideología y un movimiento político-social, aparece con el concepto moderno de la nación como respuesta AMN-107 cost una necesidad urgente de legitimar el nuevo orden político-social republicano, en el que la “soberanía del pueblo” reemplazaba al “derecho divino”
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Percebemos ent o tentando tra ar uma linha que amarre
2019-05-18
Percebemos, então, tentando traçar uma linha que amarre as discussões dos intelectuais mencionados, que as revoluções cubana e sandinista foram representadas positivamente na revista Araucaria de Chile, através de argumentos relacionados ao desenvolvimento e à popularização da cultura após haspin in
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En este exordio de la carta hoy perdida
2019-05-17
En este exordio de la carta, hoy perdida, que acompañaba la obra de Pané, se expresan todas las dudas del Almirante que, a pesar de la hipótesis de la ausencia de idolatría entre los taínos (interpretación esencial para ofrecer una representación de los indígenas que justificara su dominio), se most
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Previous studies have demonstrated localization of miR stain
2019-05-17
Previous studies have demonstrated localization of miR-21 staining in stromal thyrotropin releasing hormone of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines
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br Conclusions br Study limitations br Conflict of interest
2019-05-17
Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum s
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Dexamethasone with its anti inflammatory properties
2019-05-17
Dexamethasone, with its anti-inflammatory properties, has been shown to be an effective medication in the treatment of pain flare and is hypothesized to prevent the phenomenon as well [12]. Despite a lack of literature investigating this hypothesis, currently published phase I and II trials have pro
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br miRs and deregulation of
2019-05-17
miRs and deregulation of bone remodeling Bone remodeling can be affected by osteotropic cancers at a distance (e.g. pre-metastatic niches) or in close proximity. It has been hypothesized that osteolytic cancer angiotensin receptor blocker produce various osteolytic factors (e.g. PTHrP) that stimu
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For all analyses a P value
2019-05-17
For all analyses, a P-value Results A total of 229 patients completed the survey, representing 44% of all ICD patients presenting to the Sunnybrook Health Sciences Center ICD clinic during the study period, of which 78% reported receiving the influenza vaccine. Table 1 summarizes the characteristi
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br Discussion This study shows that the risk
2019-05-17
Discussion This study shows that the risk of all-cause mortality in patients with atrial fibrillation is directly associated with RDW in a dose-response manner. This association was independent of known risk factors of mortality. Notably, RDW is associated with all-cause mortality regardless of a
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br Methods br Results Characteristics of studies included
2019-05-17
Methods Results Characteristics of studies included in the analysis are described in the accompanying Lancet paper. We included 119 studies (58 from high-income countries and 61 from low-income and middle-income countries) in this Bisindolylmaleimide V analysis. Worldwide in 2010, an estimate
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The diagnostic infrastructure in the public sector
2019-05-17
The diagnostic infrastructure in the public sector relies mainly on sputum smear microscopy that cannot detect drug resistance. It is only when patients fail to get better on standard treatment, or have recurrence of tuberculosis, that they get screened for MDR-TB, resulting in morbidity, continued
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