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Pharmacokinetics analysis of AT on SCID
2019-05-30
Pharmacokinetics analysis of AT-406 on SCID mice bearing MDA-MB-231 tumors has shown that AT-406 achieves a maximum concentration in plasma between 1.5μM and 9.9μM, and a maximum concentration in tumor tissue between 0.5μM and 18.2μM, depending on the dose and administration route (intravenous versu
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Preference for injectable therapy over oral therapy
2019-05-30
Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne
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Poco despu s el de julio
2019-05-30
Poco después, el 19 de julio (y reimpreso en al menos siete números siguientes), se publica en la última página del mismo diario un anuncio donde de nuevo figura la América poética, esta vez entre las novedades de la mencionada librería. La acompañan ahora La guerra de las mujeres (1845) de Alejandr
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El otro paradigma cuyo alcance y magnitud exige atenci n
2019-05-30
El otro paradigma cuyo alcance y magnitud exige atención particular es la deconstrucción y todo el giro lingüístico que la precede, un enfoque en muchos sentidos inverso GS-9620 la colonialidad, aunque no en todos. Sus cauces precursores en América Latina podrían partir de figuras como Irlemar Chiam
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br Arrhythmogenic right ventricular cardiomyopathy ARVC an i
2019-05-29
Arrhythmogenic right ventricular cardiomyopathy (ARVC), an inherited heart muscle disease, is associated with a high risk of arrhythmias and sudden cardiac death . It is characterized primarily by fibrofatty replacement of the right ventricular myocardium, which is often accompanied by subsequent
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Perhaps the greatest challenge however relates to the epidem
2019-05-29
Perhaps the greatest challenge however, relates to the epidemiology of this disease and understanding the interactions that occur between the reservoir hosts (ie, monkeys), vectors, and human activities that enable transmission. Understanding these complex behavioral and ecological interactions will
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br Sebastian Vollmer and colleagues
2019-05-29
Sebastian Vollmer and colleagues (April, 2014) conclude that “the contribution of economic growth to the leukotriene receptor antagonist in early childhood undernutrition in developing countries is very small, if it exists at all”. Progress will therefore require a shift from “the so-called trick
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Since the first description of epicardial
2019-05-29
Since the first description of epicardial VT ablation with percutaneous subxiphoid access in 1996, epicardial mapping and ablation have been widely performed for the treatment of scar-related VT [55]. Svenson et al. reported that melanin inhibitor epicardial VT circuits are particularly common in p
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br Discussion We describe an additional
2019-05-28
Discussion We describe an additional diagnosis to consider when BVT is identified. One of the proposed mechanisms of BVT include elevated intracellular calcium, causing delay after depolarization in anatomically separate parts of the conducting system. Baher et al. [1] proposed that two separate
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Two years later he complained of two
2019-05-28
Two years later, he complained of two ICD shocks during a dance party. The possibility of lead fracture or electromagnetic interference was completely excluded after several examinations. Intracardiac electrograms showed that all delivered shocks were inappropriate therapies due to TWOS. The R wave
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Importa notar al mismo tiempo
2019-05-28
Importa notar, al mismo tiempo, cierta impaciencia con la indeterminación del saber celebrada hasta no hace mucho. En la ruta hacia el neoliberalismo, ese tránsito del Estado al mercado —como suele llamársele en América Latina—, la duda epistémica, el pensamiento débil, los juegos de lenguaje y la r
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Pero adem s el ejemplo nos ilustra de
2019-05-28
Pero, además, el ejemplo nos ilustra de cómo el sermón pastoral peruano no ahorra al indígena ninguno de los aspectos complejos del dogma. Pareciera que, en lo relativo phospholipase c inhibitor este punto, no importara ya aquel requisito del decoro retórico sensibilizado hacia la capacidad de su re
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vesicular monoamine transporter En una de las acciones de
2019-05-28
En una de las acciones de refriega, los indígenas alzaron vesicular monoamine transporter mano a un sargento y lo bajaron por las laderas de la montaña en el sector de Alto Berlín, donde los soldados custodiaban torres de comunicación como muestra de que no deseaban actores armados legales o ilegale
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Studies of strategies to reduce greenhouse gas emissions and
2019-05-28
Studies of strategies to reduce greenhouse gas emissions and improve health in urban environments have shown the potential to achieve both environmental and health improvements. For example, modelled effects of low emission vehicles and increased walking and cycling in London and Delhi showed major
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In a case similar to ours
2019-05-28
In a case similar to ours, presented by Seres et al. [14] in which LVNC was associated with polymorphic VT, the value of QT interval was also difficult to ascertain because of the advanced LBBB. The onset of the polymorphic VT was similar to ours, but neither pause-dependence nor post-PVB lengthenin
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