• br Methods br Results br Discussion

  2019-07-15

  

  Methods Results Discussion On the other hand, surgical patients have to some extent stress during pre- and/or post-operative period. It is well known that CRF/CRF1 receptor is involved in the activation of HPA during acute and chronic stress (Papadimitriou and Priftis, 2009, Zelena et al.,

• Table shows the comparison results of error detection rate

  2019-07-15

  

  Table 2 shows the comparison results of error detection rate of each software-based CFC technique. Each version of benchmark is injected 10000 errors. Even though the injected errors are randomized in spite of their classifications, the large number of injected errors guarantees that all types of CF

• There have been attempts to stimulate the dopaminergic

  2019-07-15

  

  There have been attempts to stimulate the dopaminergic system to influence cognition in women around menopause who have subjective complaints about their cognition by Epperson et al. (Epperson et al., 2011, Epperson et al., 2015). In perimenopausal and postmenopausal women, Epperson et al. found tha

• The main variable of the study was

  2019-07-15

  

  The main variable of the study was whether there was an association between the COMT Val158Met polymorphism and motor behavior. Additionally, it was investigated whether the effects of the COMT genotypes on the role played by tonic/phasic DA are associated with the stability/flexibility nature of t

• Another important consideration with respect

  2019-07-15

  

  Another important consideration with respect to drug conditioning suggested by the present findings is the observation of an attenuated ceramidase on the second extinction trial. Seemingly, if ERK measurements were made following a partial reduction in the conditioned response the ERK response would

• br Epac in cardiovascular pathophysiology Epac

  2019-07-15

  

  Epac in cardiovascular pathophysiology Epac orchestrates signaling actors that regulate fundamental cellular functions and general biological effects. However, some important gaps still remain in the knowledge of the physiopathological role of Epac in the heart. So far, Epac has been implicated i

• br Declaration of conflicting interests br Funding The

  2019-07-15

  

  Declaration of conflicting interests Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by CT Stem Cell grant # 15-RMB-YALE-07 (to L.E.N), and by an unrestricted Research Gift from

• Herbal products may alter the metabolism of

  2019-07-15

  

  Herbal products may alter the metabolism of certain drugs and, likewise, the metabolism of components of herbal products may be altered by some drugs, specifically those that affect cytochrome P450 LY2801653 chemical (CYP). These can bring about an alteration of the pharmacokinetics and pharmacolog

• Several main strategies for targeting E s described in the

  2019-07-15

  

  Several main strategies for targeting E3s described in the literature include: in vitro screening using functional assays [86]; computer programs for predicting potential druggable pockets, including those at protein-protein interfaces, and subsequent docking-based in silico ligand screening [87]; f

• Ergosterol The estrogen receptor ER dependent signaling path

  2019-07-15

  

  The estrogen receptor(ER)-dependent signaling pathway plays an important role in bone metabolism by restoring the balance between osteoblastic bone formation and osteoclastic bone resorption [21]. ER has two major isoforms, ERalpha (ER-α) and ERbeta (ER-β), which mediate the effect of estrogen and o

• Hinokitiol has versatile abilities as anticancer antimicrobi

  2019-07-13

  

  Hinokitiol has versatile abilities as anticancer, antimicrobial and molecule transport agents and appears to have no developmental toxicity or carcinogenic effects (Imai et al., 2006b). For anticancer activities, it causes apoptosis and ITE arrest in many different types of cancers, such as murine

• br Conclusions We can conclude

  2019-07-13

  

  Conclusions We can conclude that Arg293 is important but not indispensable for MeGlcA recognition by EcXyn30A since the R293A variant still retains activity and preference for MeGlcA-substituted substrates. The substrate specificity of GH30_8 glucuronoxylanases is most probably determined by an o

• br Conclusion The past few

  2019-07-13

  

  Conclusion The past few years have witnessed substantial progress in understanding the structural mechanisms of substrate recognition and the reactions catalyzed by the O-GlcNAc-cycling enzymes, but more work remains. In particular, future research will be needed to establish how OGT and OGA inte

• Upon assembly of HLA tetramers

  2019-07-13

  

  Upon assembly of HLA tetramers loaded with either of the two peptide versions, we could query the T cell repertoires of RA subjects and healthy individuals for the presence of cognate T Moxifloxacin weight recognizing the respective peptide-HLA complexes. We found no significant difference in frequ

• br Acknowledgments br Introduction Hypertensive retinopathy

  2019-07-13

  

  Acknowledgments Introduction Hypertensive retinopathy is a disease of the retinal microvasculature associated with elevated blood pressure (Fraser-Bell et al., 2017). Narrowing of retinal arterioles occurs in the early stage of the disease, and with persistent hypertension further vascular pat

16259 records 1014/1084 page Previous Next First page 上5页 10111012101310141015 下5页 Last page