• br Role of p MAPK

  2019-04-26

  

  Role of p38 MAPK signaling in mutated state or compromised function of p53 The tumor suppressor gene p53 functions as a central node in cellular mechanisms preserving genomic integrity in response to both genotoxic and non-genotoxic stress either by inducing apoptosis or by arresting mm concentra

• Permanent pacemaker implantation with trans IVC access was f

  2019-04-26

  

  Permanent pacemaker implantation with trans-IVC access was first reported in 23 cases by Ellestad et al., in 1980 [2]; it was then reported in 95 cases, of which the early cases were published in 1989 by the same author as the largest series reported thus far [5]. Mathur et al. also reported 27 case

• br Case An year old man with no history

  2019-04-26

  

  Case 1 An 81-year-old man with no history of purchase IOX2 disease was admitted to our hospital for the treatment of recurrent episodes of syncope after drinking. He experienced the first episode at age 75. On admission, his blood pressure (BP) was 144/81mmHg and the heart rate (HR) was 56beats/m

• Introduction Atrial fibrillation AF is the most common

  2019-04-26

  

  Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia managed in clinical practice and the most common arrhythmia requiring hospitalization [1,2]. Thromboembolism occurs with similar incidence, regardless of the form of AF [3,4]. AF management includes anticoagulation to preve

• La Constituci n espa ola

  2019-04-26

  

  La Constitución española de 1812 dispone bajo el nombre de América septentrional un territorio que desde California, Nuevo México y Texas hasta la Capitanía de Guatemala conforma una inmensa, compleja y rica estructura administrativa. Guatemala se separa poco antes de la jura de la Constitución de 1

• The multivariable analyses by Keats and colleagues identifie

  2019-04-26

  

  The multivariable analyses by Keats and colleagues identified factors associated with higher coverage of key interventions in Kenya. Current and prospective efforts tracking key indicators and their determinants over time could enable time-series regression and more sophisticated causal inference an

• br Heart rate turbulence HRT

  2019-04-26

  

  Heart rate turbulence (HRT) HRT was introduced by Schidmt in 1999 [11]. It refers to the physiological phenomenon in response to a premature beat. After a ventricular premature contraction (VPC) and a compensatory pause, there is an increase in blood pressure because of the prolonged filling. Ref

• This trial included patients who met

  2019-04-26

  

  This trial included 1500 patients, who met the ICD criteria for primary prevention (non-ischemic, ischemic, dual chamber ICD or CRT-D). The patients were randomized to 3 arms: (1) conventional therapy: Zone 1(VT) 170bpm, 2.5s delay, Zone 2 (VF) 200bpm, 1s delay; (2) high rate therapy: Zone 1(VT) 170

• Introduction Classically increased cardiac fibrosis has been

  2019-04-26

  

  Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol

• The goals are set the

  2019-04-25

  

  The goals are set; the targets laid out. The fighting is over. In just over a week\'s time, heads of state worldwide will commit to the , with its 17 Sustainable Development Goals (SDGs) and 169 associated targets. Country representatives will resolve to do everything from ending poverty and hunger

• En las relaciones pol ticas tradicionales mapuche el longko

  2019-04-25

  

  En las relaciones políticas tradicionales mapuche, el longko o autoridad tuvo la función de repartir las tierras, prerrogativa que perdió con los desplazamientos y las reducciones, situación que en unión al hecho de que los distintos gobiernos regidos por la intención del trato igualitario para los

• The patient received multiagent chemotherapy

  2019-04-25

  

  The patient received multiagent chemotherapy using cyclophosphamide, daunorubicin, vincristine, predonisolone and l-asparaginase, and high dose MTX/Ara-C, as well as the single-agent administration of nelarabine, hydroxyurea and tyrosine kinase inhibitors (TKIs) (imatinib and dasatinib). The convent

• Many of the emerging non vaccine serotypes in carriage

  2019-04-25

  

  Many of the emerging non-vaccine serotypes in carriage after PCV13 implementation (11A, 15B/C, 15A, 21, 23B, and 35F) show low potential for causing invasive disease, but some—eg, 12F, 22F, 24F, 8, and 9N—have high disease potential. Moreover, in vulnerable populations (eg, immunocompromised people)

• br Associated heart disease in children with ICD implantatio

  2019-04-25

  

  Associated iap apoptosis disease in children with ICD implantations In a multicenter ICD registry of 443 patients [8], 69% of the patients had CHD and 23% had cardiomyopathy. The most common heart disease was tetralogy of Fallot (19%), followed by hypertrophic cardiomyopathy (14%) (Fig. 3). In s

• A first step is reconsideration

  2019-04-25

  

  A first step is reconsideration of the term family planning. This debate is not simply a question of semantics—language is a powerful ideological and political statement. Discourse creates a representation of the world; it perpetuates a cultural and social reality. In this sense, language is action,

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