• There are several limitations to the

  2019-05-08

  

  There are several limitations to the procedure described herein. The present GC was developed for engaging the coronary sinus via a right-sided approach. However, this GC was bent dorsally and had the shortest tip and most acute tip angle among the Attain™ family, which facilitated its placement int

• br Material and methods br Results br Discussion

  2019-05-08

  

  Material and methods Results Discussion The present study provides clinical, molecular, and in vitro electro-physiological evidence that a rare SNP (KCNE1-D85N) can act as a genetic modifier in LQTS. In general, SNPs are thought to be non-pathological, but some have been reported to modify

• We herein report a patient

  2019-05-08

  

  We herein report a patient with dMMR and MSI-H metastatic gastric cancer who SAR405 responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1 blockade. Respon

• In this study we applied a more general approach along

  2019-05-08

  

  In this study, we applied a more general approach along these lines, which has previously been used only in few reports in the literature [8]. Based on a prospective BC database including all newly diagnosed BC cases at a large Swiss breast center over a 20-year period, we aimed to give a comprehens

• Las colaboraciones de Woinoff conforman el ltimo

  2019-05-08

  

  Las colaboraciones de “Woinoff ” conforman el último vértice de la constelación intelectual que, necessary nuestro juicio, pudo haber ayudado en el cambio intelectual de Bilbao. En ellas, el pretendido “atraso” se vuelve reserva moral desde la cual la democracia radical europea puede pensar de maner

• br Introduction Multiple signal transduction

  2019-05-08

  

  Introduction Multiple signal transduction pathways in normal and malignant Solamargine converge on Bcl-2 family proteins, which stand at the crossroads between cell survival and apoptosis. The seminal event in the intrinsic pathway of apoptosis is mitochondrial outer membrane permeabilization (M

• Although the study is of

  2019-05-08

  

  Although the study is of a high quality given the constraints of the case-control design, we question whether it alone provides sufficient evidence for this policy recommendation. Observational studies of ITNs are notoriously fraught with challenges. Even in settings in which randomised trials show

• br Discussion Variant angina was described by Prinzmetal

  2019-05-08

  

  Discussion Variant alkaline phosphatase inhibitors was described by Prinzmetal et al. in 1959 [1]. It can involve serious arrhythmias such as ventricular tachycardia, ventricular fibrillation, and atrioventricular block, and patients are particularly susceptible to sudden cardiac death in such c

• br Practical management of perioperative

  2019-05-08

  

  Practical management of perioperative anticoagulation and antiplatelet therapy in CIED surgery By integrating the current literature and the experience from our own practice, we developed a practical algorithm recently to guide the perioperative management of anticoagulation and antiplatelet ther

• Several mechanisms for cardiac involvement have

  2019-05-08

  

  Several mechanisms for cardiac involvement have been propounded as (1) direct cardiac involvement, (2) hematogenous spread, (3) lymphatic spread, (4) spreading from the venous system, such as the pulmonary vein or inferior vena cava. In cases of pericardium metastasis, most spreading routes result f

• O quilombo caracterizado como uma associa o guerreira aberta

  2019-05-07

  

  O quilombo é caracterizado como uma associação guerreira aberta, sem distinção de linhagens e transcultural. A transculturalidade vem das contribuições de povos distintos, com destaque para os imbangala. No ritual de iniciação dos imbangala, cerk circuncisão representava o rito de passagem que incor

• br The sources of cholesterol secreted into

  2019-05-07

  

  The sources of cholesterol secreted into bile Bile formation is an osmotic process and solutes are actively transported into the canaliculus by primary active lipid transporters: ABCG5/G8 for biliary cholesterol secretion, ABCB4 for biliary phospholipid secretion, and ABCB11 for biliary bile acid

• AS1404 The results described thus far suggest that PtAF

  2019-05-07

  

  The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the

• We are aware that physician

  2019-05-07

  

  We are aware that physician surveys have been previously used to assess; bisphosphonate use for bone pain [14], bisphosphonate use in metastatic breast cancer patients [15] and radiotherapy use for painful bone metastases [16] but are not aware of physician surveys being used to help design trials o

• br Material and methods br Results br Discussion

  2019-05-07

  

  Material and methods Results Discussion Previously, various small studies reported that CRT is an effective therapy in patients with NAHF [7,10–15]. These studies demonstrated favorable outcomes in patients treated with CRT, including the ability to wean patients from intravenous inotropes

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