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br Extending hospitality and strengthening relationships
2018-11-12
Extending hospitality and strengthening relationships with society Hospitality can be defined as constitutional acceptance of or receptiveness to others; this trait has played an important role in the traditional Islamic society (Sobh and Belk, 2013; Shraim, 2000). Hospitality is closely associat
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Less reconstructive methods with infective and exposed stern
2018-11-12
Less reconstructive methods with infective and exposed sternal wounds have been reported because of the challenges of dead space obliteration, infection control, and unstable hemodynamics. According to the studies reviewed, four methods have been reported for wide and open sternal wound reconstructi
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br Impact on the health of humans and other
2018-11-12
Impact on the health of humans and other animals — an opportunistic pathogen Cryptosporidium is a significant cause of diarrhoeal disease, principally in humans and livestock throughout the world. The clinical impact of the parasite is greatest in hosts whose mineralocorticoid receptor antagonist
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Seaweeds contain a variety of potentially bioactive
2018-11-12
Seaweeds contain a variety of potentially bioactive compounds some of which are not present in terrestrial plants. These compounds include, for example, proteins such as lectins or phycobiliproteins, carotenoids, pigments, polyphenols, phlorotannins and certain polysaccharides. They may have health-
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The ability to generate human vascular endothelium from iPSC
2018-11-12
The ability to generate human vascular endothelium from iPSCs is an enabling platform. Cell-based assays of endothelial function can be combined with ECs derived from iPSC lines produced from patients with genetic diseases, creating powerful model systems of human disease or associations where the p
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mu receptor antagonist There are several limitations to this
2018-11-12
There are several limitations to this technology. Fluorescence signals report relative, not absolute, membrane potentials. The temporal response results in loss of high-frequency elements and leads to a small but systematic overestimation of APD. A comparison of ArcLight and the ANEPPS dyes (Herron
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Dinitrophenol DNP is well known to be cytotoxic
2018-11-12
2,4-Dinitrophenol (DNP) is well known to be cytotoxic at high concentrations. However, recent studies have demonstrated that at low micromolar, non-toxic concentrations, DNP has neuroprotective properties in a number of in vitro and in vivo models of neurodegeneration (reviewed in (De Felice and Fer
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br Introduction Expansion of hematopoietic stem cells HSCs i
2018-11-12
Introduction Expansion of hematopoietic stem cells (HSCs) in vitro using growth factors has been thwarted by findings that there is loss of HSCs during in vitro expansion. In steady-state hematopoiesis, a majority of HSCs remain quiescent; however, in response to 5-fluorouracil (5-FU) treatment,
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The effects of TLQP on neurogenesis
2018-11-12
The effects of TLQP-62 on neurogenesis are thus similar to what is reported for antidepressant fluoxetine and serotonin (5-HT), both of which increase the proportion of undetermined Type 2a NPCs marked by Nestin+ and DCX-immunostaining and lacking the radial glial-like morphology (Boku et al., 2011;
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http www ncbi nlm nih gov eleen
2018-11-12
(http://www.ncbi.nlm.nih.gov.eleen.top/geo/query/acc.cgi?token=rfopdesiwmqiepk&acc=GSE31413) Introduction The process of differentiation of mammalian embryonic stem cells (ESCs) involves an increasing restriction in proliferative capacity (Nichols and Smith, 2009), ending in PRIMA-1MET exit in t
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FOXP labels striatal precursors and differentiated MSNs Dell
2018-11-09
FOXP1 labels striatal precursors and differentiated MSNs (Delli et al., 2013). Diverse studies thus far have attempted to pre-differentiate stem CX5461 into transplantable striatal progenitors or MSNs by using various kinds of differentiation protocols. Human ESCs were demonstrated to terminally di
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The capacity to delay cell cycle progression at
2018-11-09
The capacity to delay cell-cycle progression at the G1/S transition is central to tumor suppression by RB proteins, predominantly via interaction with, and inhibition of, the E2F family of S-phase transcriptional activators. In Drosophila, the role of Rbf proteins in cell-cycle regulation is conside
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Lead titanate provides a classical example of displacement
2018-11-09
Lead titanate provides a classical example of displacement-type ferroelectric. The crystal in paraelectric phase belongs to the space group Pm3m. At a temperature of 763 K PbTiO3 undergoes the first-kind phase transition from the cubic perovskite phase into the tetragonal ferroelectric phase which i
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Despite intense scrutiny of the
2018-11-09
Despite intense scrutiny of the harms from smoking, we are not aware of a prior study that has investigated, using data at the individual level, whether the risks of death from smoking differ across countries. We believe that such comparisons are best assessed on an additive or risk difference scale
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br Methods br Funding br Ethical clearance br Results
2018-11-09
Methods Funding Ethical clearance Results We included 89 children as described in Fig. 2, with 281 PBs, comprising 189 pairs of successive PBs (average of 3.15 biopsies per patient). Characterization features are summarized in Table 2 and details provided in Supplementary Tables 1 and 2.
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