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During cell migration GBM cells require modifying
2018-11-07
During cell migration, GBM cells require modifying their cellular volume to go through narrow spaces; these changes in volume are regulated through ionic transport (Watkins and Sontheimer, 2011). Ion co-transporters, such as the Sodium Potassium Chloride co-transporter (NKCC1) 1, regulate intracellu
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In addition to Parkinson s
2018-11-07
In addition to Parkinson\'s disease, abnormal protein faah inhibitor are also observed in several other neurodegenerative disorders, e.g. Alzheimer\'s disease, amyotrophic lateral sclerosis (ALS), polyglutamine diseases, etc., suggesting that common mechanisms underlie these disorders (Kakizuka, 19
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chemokine receptor br MALDI TOF profiling of
2018-11-07
MALDI-TOF profiling of whole sperm chemokine receptor and sub-cellular fractions All samples were analyzed by a MALDI-TOF mass spectrometer (Waters Corporation, Micromass Ltd., Manchester, UK) operating in positive linear mode as previously described [1]. Spectral profiles were collected in the 2
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br Experimental design materials and methods br Acknowledgem
2018-11-07
Experimental design, materials and methods Acknowledgements This research was funded by Région Centre (project ADRIEN) and INRA meta-program SMaCH – Sustainable Management of Crop Health (project SESAME). We are grateful to the town councils of Fleury-les-Aubrais, Saint-Jean-de-Braye, Saran an
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We examined fcMRI network changes between and months of age
2018-11-07
We examined fcMRI network changes between 6 and 12 months of age in 92 infants of whom 36 infants had both 6 and 12 month scans (128 total datasets). The current fMRI data preprocessing strategy incorporates several recent advances that minimize the impact of head motion artifact more effectively th
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It should be noted that our analyses were conducted
2018-11-07
It should be noted that our analyses were conducted in a between-subjects fashion. Previous work with adults has suggested that within- and between-subjects estimates of coupling reflect similar constructs (Schutter and Knyazev, 2012). However, this work also presents the possibility that coupling m
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A model of cortical development derived from years
2018-11-07
A model of cortical development derived from years of research in the visual system proposes that inputs to cortex compete for resources to form stable synapses (Espinosa and Stryker, 2012; Trachtenberg, 2015). The adolescent frontal cortex could be a similar battleground for competing inputs, with
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br Effects of early life stress on amygdala and striatal
2018-11-07
Effects of early life stress on amygdala and striatal development Discussion Acknowledgements This work was supported by the National Institute of Mental Health (R01MH091864 to N.T.) and the Dana Foundation (20122240). The authors would like to thank Dr. Dylan Gee for helpful comments. I
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Human infants also show learning of caregiver cues across mu
2018-11-07
Human infants also show learning of caregiver cues across multiple sensory modalities (DeCasper and Fifer, 1980; Sullivan et al., 2011), which enables them to form attachments to adoptive parents and caregivers of either sex. Although it remains unclear whether learning in human infants is the same
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These findings support the idea that the adolescent brain
2018-11-07
These findings support the idea that the adolescent purchase Sulfo-NHS-LC-Biotin is particularly vulnerable to pharmacological treatment, and that chronic fluoxetine treatment in adolescence may lead to changes in brain development that differ from the long-term adaptational changes that occur in t
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br Given the continuous improvement
2018-11-06
Given the continuous improvement of basic theories of graphics in modern times, the discipline of perspective underwent a considerable development in the 18th and 19th centuries, 70 years after the publication of Shi Xue. During this period, British and German geometricians examined the resolution
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bethanechol chloride There are many studies on antioxidant a
2018-11-06
There are many studies on antioxidant activity of A. calamus for instance, the ethanolic extract prevented acrylamide-induced hind limb paralysis, decreased GSH and GST, increased dopamine receptors in the corpus striatum [37]. Ethyl acetate and methanolic extracts (50mg/kg bw) of A. calamus was eff
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The mechanism of the system Xc increase may be linked
2018-11-06
The mechanism of the system Xc− increase may be linked to the hypoxia signaling cascade. Hypoxia increases HIF-1α which leads to an increase in multiple genes. In order to demonstrate the role of HIF-1α signaling in xCT regulation we probed blots from 10% hypoxia treated azidothymidine with HIF-1α
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br Experimental Procedures br Acknowledgments We are gratefu
2018-11-06
Experimental Procedures Acknowledgments We are grateful to Rosalind Gunby and Monica Autiero for careful reading and critical comments of the manuscript. We thank the Animal House and the Integrated Microscopy Facilities of IGB-Consiglio Nazionale delle Ricerche (CNR) and the Bioinformatic Cor
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br Results and Discussion br Author Contributions br Acknowl
2018-11-06
Results and Discussion Author Contributions Acknowledgments Introduction Specific control of cellular fate by biological surface modification has garnered recent attention for the ability to create biomimetic microenvironments (Lutolf and Hubbell, 2005). Normally, the body contains stem
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