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br miRs and deregulation of
2019-05-17
miRs and deregulation of bone remodeling Bone remodeling can be affected by osteotropic cancers at a distance (e.g. pre-metastatic niches) or in close proximity. It has been hypothesized that osteolytic cancer angiotensin receptor blocker produce various osteolytic factors (e.g. PTHrP) that stimu
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For all analyses a P value
2019-05-17
For all analyses, a P-value Results A total of 229 patients completed the survey, representing 44% of all ICD patients presenting to the Sunnybrook Health Sciences Center ICD clinic during the study period, of which 78% reported receiving the influenza vaccine. Table 1 summarizes the characteristi
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br Discussion This study shows that the risk
2019-05-17
Discussion This study shows that the risk of all-cause mortality in patients with atrial fibrillation is directly associated with RDW in a dose-response manner. This association was independent of known risk factors of mortality. Notably, RDW is associated with all-cause mortality regardless of a
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br Methods br Results Characteristics of studies included
2019-05-17
Methods Results Characteristics of studies included in the analysis are described in the accompanying Lancet paper. We included 119 studies (58 from high-income countries and 61 from low-income and middle-income countries) in this Bisindolylmaleimide V analysis. Worldwide in 2010, an estimate
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The diagnostic infrastructure in the public sector
2019-05-17
The diagnostic infrastructure in the public sector relies mainly on sputum smear microscopy that cannot detect drug resistance. It is only when patients fail to get better on standard treatment, or have recurrence of tuberculosis, that they get screened for MDR-TB, resulting in morbidity, continued
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The need for better measurement of
2019-05-17
The need for better measurement of gender empowerment cannot be understated, given that 80% of indicators to monitor SDG5 lack adequate data, often because of an absence of valid measures. Although measures of gender empowerment are available, and more are being developed, there is no consensus on t
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Permanent pacemaker implantation with trans IVC access
2019-05-16
Permanent pacemaker implantation with trans-IVC access was first reported in 23 cases by Ellestad et al., in 1980 [2]; it was then reported in 95 cases, of which the early cases were published in 1989 by the same author as the largest series reported thus far [5]. Mathur et al. also reported 27 case
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No en vano entre los a os
2019-05-16
No en vano entre los años veinte y treinta el quehacer de Aub como viajante de comercio le lleva SAR 405 realizar numerosos viajes por Europa y a conocer de primera mano, ayudado de su condición políglota, las tendencias artísticas del momento, circunstancia a la que suma su participación en los cír
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As del tercer tomo con
2019-05-16
Así, del tercer tomo, con su proyecto y horizonte interpretativo conjunto, debemos rescatar la forma de dar cuenta de las formulaciones artísticas (literarias en este caso, pero fácilmente extrapolables) como parte de una empresa sociopolítica, englobadora de lo cultural, en la cual se destaca al su
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EBV occasionally reactivates to switch its replication mode
2019-05-16
EBV occasionally reactivates to switch its replication mode from latent to lytic, producing a large number of infectious virions with the lysis of host cells [7]. Although reactivation is dangerous for the virus, its triggering factors have not yet been identified. EBV reactivation is associated not
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br Case report A years
2019-05-16
Case report A 51-years-old man visited our hospital presenting with a palpable mass over the right inguinal area which had persisted for 3 months. This lesion was approximately 3–4 cm, firm and had progressively enlarged. Laboratory data showed no remarkable anomaly except elevated lactate dehyd
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There are limitations to the current study
2019-05-16
There are limitations to the current study. As with all surveys, there is an inherent bias in those that are contacted and in those that respond. Obtaining 90 responses on this topic is clearly important, however, the study would be strengthened by a greater number of responses. In addition, the maj
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ER provides the clinician with a rapid and
2019-05-16
ER-2000® provides the clinician with a rapid and accurate assessment of a patient׳s arrhythmia, improving clinical decision making and clinical outcomes. Further large-scale study is warranted to confirm the accuracy of ER-2000®. Furthermore, the efficacy and usefulness of ER-2000® should be examine
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Introduction The heart beat provides the mechanical force fo
2019-05-15
Introduction The heart beat provides the mechanical force for the pumping of oxygenated blood to, and deoxygenated blood away from, the peripheral tissues [1]. This depends critically on the orderly activation and recovery of electrical excitation through the myocardium. Disruptions of this can lea
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The approach used of estimating effectiveness relative to a
2019-05-15
The approach used, of estimating effectiveness relative to a matched counterfactual, can be regarded as an attempt to reach the ideal estimation of relative risk, namely the comparison of a population to itself with the exposure removed. However, it is not possible to know exactly what would have ha
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