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br Introduction Skeletal muscle development is
2018-10-31
Introduction Skeletal muscle development is carried out by a reservoir of progenitor cells, which differentiate and fuse into multinucleated syncytia during several distinct but overlapping stages: early embryonic, mid-late embryonic, fetal, perinatal and adult (for review see Tajbakhsh, 2009). F
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In the last couple of years several craniofacial NCSC popula
2018-10-31
In the last couple of years several craniofacial NCSC-populations within the head were described. Such jak stat inhibitor were identified e.g. within the dental pulp and the periodontal ligament (Arnold et al., 2010; Waddington et al., 2009; Widera et al., 2007). Importantly, adult stem cells tend
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Recent publications provide inconsistent results whether the
2018-10-31
Recent publications provide inconsistent results whether the overexpression of KLF4 is consistently accompanied with a more favorable outcome in all gastrointestinal cancer types. In HCC the cholinesterase inhibitor pattern of KLF4 is significantly increased compared to corresponding adjacent non-t
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Of particular relevance to the results presented in
2018-10-31
Of particular relevance to the results presented in our study was the differentiation of mesoderm from hESCs via 5 days of 5 μM CHIR treatment (Tan et al., 2013). Intermediate to the desired cell types, CHIR treatment caused a marked upregulation of T mRNA and protein levels, similar to our findings
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Based on their in vitro characteristics and
2018-10-31
Based on their in vitro characteristics and gene expression profile, it is plausible that CB-iNCs contain an amplifying neural population that can be expanded under chemically defined conditions and primed to differentiate into more committed progenitors. This population presents similarities with t
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br Discussion In this study we demonstrated
2018-10-31
Discussion In this study, we demonstrated the long-term in vitro maintenance and expansion of primary-sphere-derived CD24hi/CD29hi cells. These rna helicase retained their ability to self-renew and remained fully functional upon transplantation. In addition to our in vivo experiments, we have dev
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PSA NCAM targeted cell sorting from neural rosettes allowed
2018-10-31
PSA-NCAM-targeted cell sorting from neural rosettes allowed an isolation of NCSC populations. Compared to the previously defined hPSC-derived NCSCs, p75+/HNK1+ cells, PSA-NCAM− Talabostat mesylate cost exhibited similar molecular characteristics and multipotentiality; i.e., both were able to genera
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Cancer cells use epigenetic mechanisms to control tumor
2018-10-31
Cancer Cy5.5 NHS ester use epigenetic mechanisms to control tumor growth, invasion, and resistance to therapy. Novel therapeutic approaches targeting epigenetic modifications are considered the new frontier in cancer therapy. In fact, pharmacological modulation of epigenetic alterations is expected
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Comparative analysis of transgenic hPAX GFP
2018-10-31
Comparative analysis of transgenic hPAX6GFP expression revealed similarities between the retinal organoid system and the mouse retina in vivo. Our analyses indicated a similar sequence of hPAX6GFP+ retinal cell types in mice in vivo, and in mESC- and hESC-derived retinal organoids: progenitors and r
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ASXL belongs to the enhancer of
2018-10-31
ASXL1 belongs to the enhancer of trithorax group (TrxG) and polycomb group (PcG) (ETP), and genetically interacts with CBX2 in mice (Fisher et al., 2010). PcG and trxG proteins are key regulators for the expression of numerous developmental genes by silencing or activating gene expression, respectiv
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br Experimental Procedures br Author Contributions
2018-10-31
Experimental Procedures Author Contributions Acknowledgments Introduction Tissue engineering technology has become one of the most promising therapeutic approaches for bone regeneration in bone defects (Zou et al., 2011; Ye et al., 2011; Xiao et al., 2011). As a source of mesenchymal st
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where the value of the
2018-10-30
where the value of the parameter is determined by the focusing angle , and () is the arbitrary dependence satisfying the condition () ≠ 0. Let us list as an example the potentials implementing the above-described arrival function at =0, 1, 2 and at ()=1: where was determined earlier in formula
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br Vacancy impurity interactions in
2018-10-30
Vacancy – impurity interactions in the aluminum lattice The supercell contained 2×2×2 cubic unit cells of the FCC aluminum lattice. The calculations were performed using an energy cutoff of 600eV for the plane-wave basis set and 2×2×2 k-points grid in the Brillouin zone. Such a choice of the main
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br Previous research on informal care provision and
2018-10-30
Previous research on informal care provision and health Previous studies exploring the link between provision of informal care and health reflect the complexity of researching this topic area. Cross-sectional analyses may be limited in examining the factors preceding or following an individual\'s
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br Data and methods br Results Table summarizes the
2018-10-30
Data and methods Results Table 1 summarizes the characteristics of the full sample and by gender. Table 2 shows results from 9 linear regression models of the three biomarker indices for the full sample and by gender. The coefficients associated with covariates (age, gender, race/ethnicity, a
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