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The finding of an aortic phenotype in
2018-11-05
The finding of an aortic Tenofovir Disoproxil Fumarate in a mouse model with a complete Smad3 deficiency very similar to the human disease supports the idea that also lack of functional SMAD3 could cause the human clinical phenotype. A similar scenario has been described for the TGF-β2 mouse model
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Most chemotherapeutic drugs used clinically evoke cell apopt
2018-11-05
Most chemotherapeutic drugs used clinically evoke cell apoptosis by inducing DNA damage. However, the high efficiency of DNA repair due to the overexpression of DNA repair proteins in cancer thymidylate synthase inhibitors reduces the drug efficacy significantly (Fink et al., 1996, 1998). For examp
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Our first goal therefore is
2018-11-05
Our first goal therefore is to assess what kinds of CSR initiatives developed by companies have more impact on consumer satisfaction. It might argue that the different nature of CSR initiatives undertaken by a company will have a specific influence on the CSR consumer response mechanism (Carroll, 19
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Study based on a goal driven survey
2018-11-05
Study 2, based on a goal driven survey supplemented Study 1 and shows two mechanisms that influence CSR consumer satisfaction, one directly and the other indirectly through the mediation of brand attitude. The results confirm the direct influence of CSR on customer satisfaction, and Baron and Kenny\
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In summary it is clear that the
2018-11-05
In summary, it is clear that the Late Cretaceous is a major episode of magmatic activities and the related large scale Sn–W mineralization distribute throughout the southeast Yunnan and northeast Vietnam. Combining the new data of this study and published igneous rocks and mineralization ages (Appen
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Sleep deprivation per se is associated with
2018-11-05
Sleep deprivation per se is associated with HPA axis hyperactivity and negatively affects glucose tolerance [16]. The mechanism involved in impaired glucose metabolism following changes in the sleep–wake cycle seems to be the decreased efficacy of the negative feedback regulation of the HPA axis [42
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A recent review considers in
2018-11-05
A recent review considers in detail the reasons why these parameters are effective for inducing stepping [1], but will not be considered here. Briefly, beta/gamma oscillations in every PPN cell are mediated by high threshold, voltage-dependent N- and P/Q-type calcium channels [42]. We discovered tha
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br Description and operation of the system
2018-11-05
Description and operation of the system Fig. 1 reports a cross section of the technological part of the proposed system. It includes: Furthermore, the photosensors aligned with the micro-channel can monitor the chemiluminescent reactions [25] as well as bioluminescent reactions. Using an externa
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br Methods The list of
2018-11-05
Methods The list of used reagents can be found in Supplementary information. Results and discussion Conclusion We have devised a novel gold nanoparticle based colorimetric glycosylase for the detection of E. coli bacteria in urine of UTI patients. The sensor was constructed by conjugating
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Kendirci and colleagues performed bilateral CN crush injury
2018-11-05
Kendirci and colleagues performed bilateral CN crush injury in rats and injected bone marrow‐derived MSC (BM‐MSC) and BM‐MSC selected for p75‐nerve growth factor receptor expression in the corpus cavernosum, resulting in beneficial effects on erectile recovery [5]. These authors suggested paracrine
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The IgY antivenom CDR sequences were determined
2018-11-03
The IgY antivenom CDR sequences were determined from immunized B cells by amplification of VL and VH chain genes, preparation of IgY chain double-strand cDNAs, and clonal selection and sequencing of hyper-variable regions of IgY genes. The obtained sequences were submitted to Blast analysis, and the
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product br Material and methods br Results br Discussion
2018-11-03
Material and methods Results Discussion This investigation adds several novel insights into the role of SES in attention and memory dynamics in infancy. First, SES had little influence on mechanisms of attention orienting in infancy, consistent with results from a similar investigation in c
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Findings from the current study should
2018-11-03
Findings from the current study should be interpreted in light of three core limitations. First, we did not detect significant threat bias using reaction time data from the dot-probe task. This limits our ability to interpret the present data as a function of individual patterns of attention bias. P
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Recently Noble and colleagues reported socioeconomic dispari
2018-11-03
Recently, Noble and colleagues (2015) reported socioeconomic disparities in both language and declarative memory emerging between 15 and 21 months of age. Both language and memory show individual differences in developmental trajectories in the first two years of life (Barr et al., 1996; Barr and Br
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Despite the limitations this is
2018-11-03
Despite the limitations, this is the first study to our knowledge to document differences in the associations between ack1 inhibitors function and visuospatial memory performance in healthy young adults as a function of childhood income levels. We used prospective data collection over the course of
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