• br Autophagy and lipid metabolism LD formation is an

  2019-06-18

  

  Autophagy and lipid metabolism LD formation is an indispensable step in lipid metabolism. The Atg8/LC3 conjugation system is essential for autophagosome membrane formation. However, some evidence suggests that Atg8/LC3 conjugation is also involved in LD formation. Indeed, LD formation is suppress

• Maharaj K Bhan s accompanying Comment correctly identifies t

  2019-06-18

  

  Maharaj K Bhan\'s accompanying Comment correctly identifies that the main need is to obtain estimates on cause-specific mortality that are specific to each district. In particular, improved understanding is needed of how three causes, which account for 80% of neonatal deaths (birth asphyxia or traum

• Baseline WBC count and baseline measures of hepatic

  2019-06-18

  

  Baseline WBC count and baseline measures of hepatic and renal function for responders and nonresponders are shown in Table 1. No relationship was evident between responders to decitabine or treatment choice and baseline WBC counts, or between responders and baseline measures of hepatic function (ALT

• In recent years the impact that food production

  2019-06-18

  

  In recent years, the impact that food production and consumption have had on the environment has received increasing international attention. Some food production practices and consumption behaviours are putting the environment under a great stress, contributing to climate change. The food sector ac

• Second political regime does very little to explain

  2019-06-18

  

  Second, political regime does very little to explain differences between countries. Rwanda, Congo (Brazzaville), and Tanzania have very similar child mortality rates (between 40 and 60 deaths per 1000 livebirths in 2014) to South Africa, Botswana, and Namibia despite the former countries being consi

• br Conventional mapping and ablation of ventricular tachycar

  2019-06-18

  

  Conventional mapping and ablation of ventricular tachycardia Substrate mapping during sinus rhythm Technical issues Conclusion Conflict of interest Introduction By eliminating the arrhythmogenic focus, catheter ablation can be a curative therapy of ventricular tachyarrhythmias (VTA

• The fact that interstitial pneumonia was induced at a

  2019-06-18

  

  The fact that interstitial pneumonia was induced at a low dose of bepridil (100mg/day) supports an immunoallergic mechanism rather than a pulmonary toxicity mechanism. In the present case, the dose of bepridil was lower than those in previously reported cases (150–400mg/day) [3] and it was given for

• Examples of numerically generated vortices

  2019-06-18

  

  Examples of numerically generated vortices and their organizing centers in 3-D excitable media are illustrated in Fig. 1. Panels a to d show 4 different configurations of 3-D scroll waves that were computed using the FitzHugh–Nagumo model [39,40]. Panel a shows an example of the simplest configurati

• The efficiency of additional strategies for

  2019-06-18

  

  The efficiency of 2 additional strategies for eliminating the substrate for AF maintenance in addition to PVI has been described. Linear lesions are commonly made at the roof between the contralateral superior PVs (roof line), and at the isthmus between the mitral valve and the left inferior PV (mit

• br Conclusions br Conflict of interest br Introduction Gastr

  2019-06-18

  

  Conclusions Conflict of interest Introduction Gastrointestinal stromal tumor (GIST) arises from the mesenchymal tissue of the gastrointestinal tract. The annual incidence of this condition is 7 cases per million people in the West. However, the incidence could in fact be higher in Asian pop

• Recently denosumab demonstrated a significant delay in the

  2019-06-18

  

  Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R

• To date over mutations in KCNQ

  2019-06-18

  

  To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [

• Ginsenoside Rd cost One of the lessons the global health com

  2019-06-18

  

  One of the lessons the global health Ginsenoside Rd cost learned from its experience with HIV was the need to rapidly identify individuals who are eligible for treatment. Yet HCV is severely underdiagnosed ( Lancet Glob Health —The following sentence should have read “Alarmingly, almost half of bo

• Silydianin We report a case of DCML deficiency and

  2019-06-18

  

  We report a case of DCML deficiency and MDS in a patient with GATA2 mutation who successfully underwent allogeneic stem cell transplantation. Case report At presentation, she had adapted to a hemoglobin level of 79g/l and had only occasional discrete symptoms of her anemia, as fatigue, other con

• br Conflict of interest br Introduction Idiopathic left vent

  2019-06-17

  

  Conflict of interest Introduction Idiopathic left ventricular tachycardia (ILVT) with a right bundle-branch block (RBBB) configuration and superior or left axis is a distinct entity that arises in the left ventricle, mostly because of a reentry mechanism and is usually verapamil sensitive [1–6

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