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br After several decades of community based interventions an
2019-06-21

After several decades of community-based interventions and surveillance, on Nov 15, 2016, Morocco was recognised by WHO as having eliminated trachoma as a public health problem. A formal ceremony, involving the handover of a letter of recognition from Margaret Chan, WHO\'s Director-General, marked
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br In the past year
2019-06-21

In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm
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In the APHRS survey most respondents
2019-06-21

In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate
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br Conclusions Implantable monitoring devices have become hi
2019-06-21

Conclusions Implantable monitoring devices have become highly useful diagnostic tools for AT/AF [32]. However, the accuracy of the obtained diagnostic information is influenced by several factors, including the presence of non-AT/AF events, such as RNRVAS or PMT, caused by VA conduction or by sub
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br Materials and methods br Results br Discussion Utilizing
2019-06-21

Materials and methods Results Discussion Utilizing IHC, the majority of OS samples were positive for RANKL (68%), with RANKL staining detectable in OS tumor Protease Inhibitor Cocktail (EDTA-Free, 200X in DMSO) and tumor anaplastic cells. However, a wide range of RANKL expression within the
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The GCT usually involves a cladding that consisted of
2019-06-21

The GCT usually involves a cladding that consisted of reactive bone and fibrosis, with a distinct boundary surrounded by soft tissue. Nevertheless, the active cladding is very thin among patients with severe invasiveness, including tumors that extend directly in into the muscle and fat, or other sig
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br Conflict of interest br Acknowledgments br
2019-06-21

Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide AG-120 manufacturer pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the human gen
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It is noteworthy that in
2019-06-21

It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex
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br Conclusions br Disclosures br
2019-06-21

Conclusions Disclosures Funding Sources Introduction Pulmonary vein isolation (PVI) has become an accepted treatment for atrial fibrillation (AF) [1]. The efficacy of PVI is sometimes insufficient, and atrial substrate modification of target specific AF signals indicating the substrate r
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br Conflict of Interest br Acknowledgments br Introduction H
2019-06-21

Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi
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br A tactical change in research and advocacy is needed
2019-06-21

A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di
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br En general los resultados electorales
2019-06-21

En general, los resultados electorales de 2011 demuestran la identificación y cercanía lograda entre los movimientos sociales y Ollanta Humala, por lo menos en términos de adhesión electoral, la misma que se mantuvo en el tiempo pues en 2006 también estos sectores le otorgaron su voto. Así, la ele
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Bernardo Ar valo de Le
2019-06-21

Bernardo Arévalo de León señala que en Guatemala la dsn no alcanzó el nivel de desarrollo conceptual que tuvo en otros países como Chile, Brasil y Argentina. Del mismo modo, el general Héctor Alejandro Gramajo Morales, un teórico de la dsn en Guatemala, indicó que si bien el concepto de seguridad na
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In patients with typical atrial flutter circulating around
2019-06-20

In patients with typical atrial flutter circulating around the tricuspid valve, the verification of a bidirectional conduction block is recommended for cavotricuspid isthmus (CTI) ablation, because a unidirectional conduction block at the CTI has been previously reported to cause recurrence of atria
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br Discussion We herein report a case
2019-06-20

Discussion We herein report a case of inappropriate shock therapy that was caused by T-wave oversensing and that occurred when the patient had sinus tachycardia and was squatting. Several methods were considered to troubleshoot this problem. We decreased the sensitivity and increased the NID and
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